Case Report

Primidone and neuroleptic malignant syndrome; a case report

Volume 52 · Issue -1 Publish Date: January 1, 2014
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Seden Demirci
Süleyman Kutluhan
Kadir Demirci
Arif Demirdaş
Demirci, S., Kutluhan, S., Demirci, K., & Demirdaş, A. (2014). Primidone and neuroleptic malignant syndrome; a case report. Neuropsychiatric Investigation, 52(-1), 32–4. https://doi.org/10.5455/NYS.20141009063956
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Abstract

Neuroleptic malignant syndrome (NMS) is a rare but potentially fatal complication of treatment with antipsychotic drugs. Clinical features of NMS are muscle rigidity, hyperpyrexia, autonomic instability, mental status changes, and high level of creatine phosphokinase. Primidone is an antiepileptic drug and also used for the treatment of essential tremor. It may interact with many drugs such as antipsychotics. This report presents a 49-year-old patient who developed NMS following the abrupt discontinuation of primidone.

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Article Info
Published In
Journal Neuropsychiatric Investigation
Volume / Issue Volume 52 · Issue -1
Pages 32-4
History
Published Online January 1, 2014
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Seden Demirci
Süleyman Kutluhan
Kadir Demirci
Arif Demirdaş
Cite this Article
Demirci, S., Kutluhan, S., Demirci, K., & Demirdaş, A. (2014). Primidone and neuroleptic malignant syndrome; a case report. Neuropsychiatric Investigation, 52(-1), 32–4. https://doi.org/10.5455/NYS.20141009063956
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